Feline Health Marker Yakasanganiswa Kuonekwa (5-6 zvinhu)

【Kuedza chinangwa】
Feline pancreatic lipase (fPL) : The pancreas ndiyo yechipiri yakakura kugaya gland mumuviri wemhuka (yekutanga chiropa), iri pamberi pedumbu remuviri, yakakamurwa kuita kuruboshwe nekurudyi lobes.Basa rayo guru nderokubudisa ma enzymes anodiwa kumuviri.Pancreatitis yakakamurwa kuva acute pancreatitis uye chisingaperi chirware.Kukuvadzwa kunokonzerwa neiyo yekutanga kunowanzo kuve kwechinguvana, nepo yekupedzisira ichisiya zvachose fibrosis uye atrophy mukati menguva yekuzvimba kusingaperi.Pakati pavo, chisingaperi pancreatitis inokwana 2/3 yekatsi pancreatitis.
Cholyglycine (CG) imwe ye conjugated cholic acids inoumbwa nekubatanidzwa kwecholic acid uye glycine.Glycocholic acid ndiyo inonyanya kukosha bile acid chikamu muserum panguva yekuzvitakura.Apo masero echiropa akakuvadzwa, kutorwa kweCG nemasero echiropa kwakaderera, zvichiita kuti kuwedzera kweCG content muropa.Mu cholestasis, kubuda kwecholic acid nechiropa kunokanganisa, uye zvinyorwa zveCG zvakadzokera kuropa rinowedzera, izvo zvinowedzerawo zvinyorwa zveCG muropa.Bile acids inochengetwa mu gallbladder, iyo inogona kubviswa. kuburikidza nehepatic duct mushure mekudya.Saizvozvo, zvirwere zvechiropa uye bile duct kuvharika zvinogona kukonzera iyo isiriyo index.
Cystatin C imwe yemapuroteni e-cystatin.Iyo inonyanya kukosha yemuviri basa ndeyekugadzirisa basa re cysteine ​​protease, iyo ine yakasimba inhibitory effect pa cathepsin B, papain, figs protease, uye cathepsin H uye ini yakabudiswa ne lysosomes.Inobata basa rakakosha mumetabolism ye intracellular peptides uye mapuroteni, kunyanya mumetabolism ye collagen, iyo inogona hydrolyze mamwe prehormones uye oaburitsa mumatanho anotambwa kuti atambe mabasa awo ehupenyu.Hereditary cerebral hemorrhage ine amyloidosis chirwere chakanangana ne cystatin C gene mutation, iyo inogona kukonzera cerebral vascular rupture, cerebral hemorrhage uye mamwe migumisiro yakakomba.Itsvo ndiyo chete nzvimbo yekujekesa inotenderera cystatin C, uye kugadzirwa kwe cystatin C kunogara.Iyo serum cystatin C level inonyanya kuenderana neGFR, inova yakanaka endogenous marker kuratidza shanduko yeGFR.Iko kushanduka kwemukati meimwe mvura yemuviri inobatanidzwawo nemhando dzakasiyana dzezvirwere.
NT-proBNP (N-terminal pro-brain natriuretic peptide), inozivikanwawo seB-type diuretic peptide, iprotein hormone inovanzwa ne cardiomyocytes mumaventricles emwoyo.Kana ventricular blood pressure ichiwedzera, ventricular dilation, myocardial hypertrophy, kana kuti kumanikidzwa kwemyocardium kunowedzera, iyo inotangira ye NT-proBNP, proBNP (inosanganisira 108 amino acids), inobudiswa muropa ne cardiomyocytes.
Katsi allergen yakazara IgE (fTIgE) :IgE imhando yeimmunoglobulin (Ig) ine huremu hwe188kD uye yakaderera zvakanyanya muserum.Inowanzo shandiswa kuongororwa kweallergic reactions.Mukuwedzera, inogonawo kubatsira mukuongororwa kwehutachiona hwehutachiona uye multiple myeloma.1. Allergic reaction: kana allergic reaction ikaitika, inotungamirira kukuwedzera kwe-allergen LgE.Iyo yakakwira iyo allergen LgE, iyo yakanyanya kukomba iyo allergic reaction.2. Chirwere cheparasite: mushure mokunge chipfuwo chabatwa nemaparasite, iyo allergen LgE inogonawo kuwedzera, iyo inowanzoenderana nehunyoro hunokonzerwa nemapuroteni eparasite.Pamusoro pezvo, kuvepo kwakashumwa kwegomarara kunogonawo kubatsira mukukwira kweIgE yakazara.
【Kuona musimboti 】
Ichi chigadzirwa chinoshandisa fluorescence immunochromatography kuona muhuwandu hwemukati wefPL/CG/fCysC/fNT-proBNP/fTIgE muropa rekati.Chinhu chakakosha ndechekuti nitrocellulose membrane yakanyorwa nemitsara yeT neC, uye mutsetse weT wakavharwa neantibody a inonyatsoziva antigen.Iyo inosunga padhi inopfapfaidzwa neimwe fluorescent nanomaterial yakanyorwa antibody b inogona kunyatso ziva iyo antigen.Masoja ekudzivirira chirwere ari mumucherechedzo anosunga kune chero nanomaterial yakanyorwa kuti antibody b kuita yakaoma, iyo inobva yasunga kuT-line antibody A kuti igadzire masangweji.Kana mwenje wekusimudzira wakadzimwa, iyo nanomaterial inoburitsa masaini efluorescent.Kusimba kwechiratidzo kwaive kwakabatana neiyo antigen concentration mumuenzaniso.